MPP 157® | Muscle Performance Peptides | Hi-Tech Pharmaceuticals

• A muscle growth peptide supplement combining three recovery compounds
• Leu-Pro-Ile tripeptide (LI-157®), Sustamine®, and HMB
• Supports muscle protein synthesis and muscle recovery
• Formulated to support tissue repair after resistance training
• Best taken alongside a complete protein source

MUSCLE PERFORMANCE PEPTIDES

MPP 157® (also known as Muscle Performance Peptides®) combines three peptide and amino acid compounds formulated to support muscle growth and recovery in the tendons, ligaments, muscles, and gut. It is built to support protein synthesis and muscle recovery after hard training. The first compound is a tripeptide (Leucyl-Prolyl-Isoleucine) under the brand name LI-157®, used by athletes for its musculoskeletal support, including exercise recovery and tissue repair. By supporting accelerated recovery, MPP 157® is formulated to help athletes adapt to training stimuli more effectively.

The second peptide is Sustamine®, a branded form of L-alanyl-L-glutamine, a peptide pairing the amino acids L-glutamine and L-alanine. It is designed to support endurance, muscle recovery, and electrolyte and water absorption more effectively than standard L-glutamine alone. It combines L-glutamine, which supports muscle protein synthesis, and L-alanine, which the body uses to rebuild glycogen stores.

MPP 157® also contains HMB (beta-hydroxy-beta-methylbutyrate), a natural compound the body makes when it breaks down the amino acid leucine. HMB helps reduce muscle protein breakdown, supports muscle growth and muscle strength, and supports recovery after hard exercise. HMB has been known for its effects on muscle protein synthesis, strength, recovery, and lean body mass, particularly in older adults and people starting a new resistance training routine.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

How the Leu-Pro-Ile Tripeptide Works

MPP 157® is built around Leucyl-Prolyl-Isoleucine (Leu-Pro-Ile), a specific peptide made of three amino acids: leucine, proline, and isoleucine. Its anabolic potential comes from how it is processed by the body. The main mechanism is its ability to activate the mTORC1 (mechanistic target of rapamycin complex 1) pathway, which signals muscle cells to build new proteins. Leucine is recognized as a key trigger of muscle protein synthesis, and isoleucine works alongside it to support glucose uptake and energy use in skeletal muscle. Proline gives the peptide structural stability and resistance to breakdown by digestive enzymes, which allows more intact peptides to reach the bloodstream and deliver its signal to muscle tissue.

Sustamine®, developed by Kyowa Hakko Bio Co., Ltd., is L-Alanyl-L-Glutamine, a stable dipeptide of L-Alanine and L-Glutamine, and is absorbed more easily than complex protein molecules, which makes it useful for hydration, endurance, and recovery. It supports the body in three ways: replacing lost electrolytes and fluids, supporting muscle repair, and refilling energy stores.

HMB is a natural metabolite of leucine that supports muscle protein balance, strength, and recovery. It was included in MPP 157® for its complementary role alongside the two peptides.

To get the most from MPP 157®, take it alongside a complete protein source like Precision Protein®, HumaPro®, or Precision EAA®, so the signaling pathway has the dietary proteins and building blocks it needs to build new muscle tissue.

What to Know About Muscle Peptides

• What a Peptide is: A peptide is a short chain of amino acids. Peptide supplements like the ones in MPP 157® are taken to support muscle growth and recovery, and they work best alongside proper nutrition and training.
• Peptides vs Collagen: This is different from collagen peptides, which support skin and connective tissue. MPP 157® is built for muscle mass and lean muscle support rather than collagen.
• Peptides and Growth Signaling: The peptide hormones and growth factors the body uses for muscle growth respond to training and nutrition. MPP 157® supports that process from the nutrition side, supplying specific peptides and HMB that signal muscle protein synthesis alongside your diet.
• Who it Suits: Lifters focused on muscle recovery and protein synthesis, and anyone, including older adults, looking to support lean body mass alongside resistance training.
• How to Use it: Pair it with enough dietary protein, since the peptides provide the signal while protein provides the building blocks. Consistency over weeks matters more than any single dose.